Association between COVID-19 vaccines and herpes zoster and urticaria: a UK population-based self-controlled case series study
Publication Date
August 21, 2026
Description
Results of additional analyses referenced in the publication.
Additional analyses included:
(i) assessing the influence of SARS-CoV-2 infection on the investigated associations by restricting the study population to those who had an infection within 2 months preceding the first vaccine dose (SCCS_COVIDAnalysis.xlsx),
(ii) restricting HZ cases to those who had a zoster vaccination prior to the first COVID-19 vaccine dose because it may reduce the risk of HZ (SCCS_VZVAnalysis.xlsx),
(iii) restricting HZ cases to those who did not receive immunosuppressants, antibiotics, or systemic corticosteroids as they may increase the risk of HZ (SCCS_IMAnalysis.xlsx),
(iv) extending the exposure window by adding 7 days to pre- and post-vaccination periods to account for delay in diagnosis recording (SCCS_ExtendedPeriodAnalysis.xlsx).
Subjects (JACS)
Subjects (LC)
Divisions
Data type
Numeric
Funders
NIHR School for Primary Care Research
Grant Number
Project No: 684, Funding round: FR 8
Data collection method
Aggregation
Legal and ethical issues
The study received ethical review through the Clinical Practice Research Datalink’s Research Data Governance process, which approved its protocol (protocol reference ID: 23_003023). This study is based in part on data from the Clinical Practice Research Datalink obtained under licence from the UK Medicines and Healthcare products Regulatory Agency. The views expressed are those of the author(s) and not necessarily those of the NIHR or the Department of Health and Social Care. The data is provided by patients and collected by the NHS as part of their care and support. The interpretation and conclusions contained in this study are those of the author/s alone. Copyright© (2026), re-used with the permission of The Health & Social Care Information Centre. All rights reserved. The data presented are additional results from the study’s statistical analyses and cannot be used to identify individuals.
Resource languages
English (UK)
Publisher
University of Nottingham
Date Issued
August 20, 2026
Except where otherwise noted, this item's license is described as
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Name
SCCS_ExtendedPeriodAnalysis.xlsx
Size
15.43 KB
Format
Microsoft Excel XML
Checksum (MD5)
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Name
SCCS_COVIDAnalysis.xlsx
Size
20.36 KB
Format
Microsoft Excel XML
Checksum (MD5)
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