Processing and properties of PLA-HA nanocomposites: the effect of particle morphology and dispersants
Publication Date
March 25, 2016
Description
The load bearing capacity of biodegradable polymeric medical devices remains limited; an improvement in mechanical properties is desirable to widen the range of applications. Incorporation of nanoparticles is explored to increase the mechanical properties of the base matrix whilst maintaining desirable polymeric processing routes. Various nanomaterials have been investigated for polylactic acid (PLA) reinforcement for orthopaedic applications; hydroxyapatite (HA), the main inorganic constituent of bone, is one of the most promising bioresorbable nanofillers. However, uncoated nanoparticles agglomerate easily during compounding; tailored coatings can offer new opportunities to improve dispersion.
This study investigates the effectiveness of novel tailored dispersants on particle dispersion, rheological properties and on macroscopic mechanical properties, when coated onto HA nanoparticles (HANP). The dispersants consist of short-chain PLA with isosorbide head groups (isPLA), or neat dodecenylsuccinic anhydride (DDSA).
HANP were synthesised via a hydrothermal counter-flow process with dispersant coatings added in-situ. Neat DDSA was purchased whilst isPLA was polymerised via a standard ring-opening route involving lactide, a tin catalyst and isosorbide initiator. Nanocomposites were compounded in a twin-screw recirculating extruder and assessed by TEM, rheology and mechanical measurements.
Parent projects:
Integrated Molecular Design of Melt-processable Bioresorbable Engineering Nanocomposites for Health-Care (BENcH)
Collection dates:
Aug. 2014 - Mar. 2016
External URI
Subjects
Subjects (JACS)
Subjects (LC)
Divisions
Faculties, Schools and Departments::University of Nottingham, UK Campus::Faculty of Engineering::Department of Mechanical, Materials and Manufacturing Engineering
Data type
Excel files for: Melt compounding, Mechanical Testing, GPC, TGA
Grant Number
EP/J017272/1
Data collection method
Software
Resource languages
English
Publisher
The University of Nottingham
Date Issued
March 31, 2016
File(s)![Thumbnail Image]()
![Thumbnail Image]()
Name
GPC.xls
Description
GPC
Size
98.5 KB
Format
Microsoft Excel
Checksum (MD5)
4abaee8952866b8b9c090165105dc4be
Name
Mechanical Testing.xls
Description
Mechanical Testing
Size
5.13 MB
Format
Microsoft Excel
Checksum (MD5)
1121c462727895b5e8e54bd6f65af3bc