Nigrosome depigmentation as seen on neuromelanin-sensitive MRI at 3T as diagnostic marker in clinical uncertain parkinsonism: analysis plan for the secondary aims of N3iPD study
Publication Date
December 1, 2023
Creators
Description
Access to these files may be requested. Please contact Dr Xing at You.Xing@nottingham.ac.uk. In our prospective multi-centre MRI study at 3T, our primary aim was to establish the prospective diagnostic value of iron-sensitive susceptibility-weighted MRI of the substantia nigra in clinical uncertain Parkinsonism. We predefined depigmentation measured by neuromelanin-sensitive MRI scans (Trial registration number NCT03022357) as a secondary aim. This document details the research questions, hypotheses and analysis plan related the neuromelanin-MRI.
Parent projects:
Trial registration number: NCT03022357
Associate publ. DOI
Related resources
Subjects (MeSH)
Subjects
Subjects (JACS)
Subjects (LC)
Divisions
University of Nottingham, UK Campus::Faculty of Medicine and Health Sciences::School of Medicine
Corporate collaborators
N3iPD team: Saadnah Naidu, Tayyib Hayat, Halim Abdul-Sapuan, Stefan Schwarz, Nin Bajaj, Jonathan Evans, Antonio Martin-Bastida, Marta Gennaro, Andreas-Antonios Roussakis, Paola Piccini, Jim Birchall, Rob Skelly
Data type
Protocol
Funders
Funders
Michael J. Fox Foundation
Grant Number
11473
Data collection method
Data analysis plan
Resource languages
English
Publisher
The University of Nottingham
Date Issued
December 1, 2023
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Name
statisticalplanforN3iPDdraft.pdf
Description
analysis and statistical plan
Size
185.43 KB
Format
Adobe PDF
Checksum (MD5)
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