Elucidating the molecular landscape of the stratum corneum
Publication Date
March 18, 2022
Description
• Characterization of the molecular structure of skin, especially the barrier layer, the stratum corneum using 3D OrbiSIMS.
• Understand the chemical variations relating to fundamental biological processes, such as the epidermal cholesterol sulfate.
• Investigate the non-homogeneity of the stratum corneum, both laterally and as a function of depth. Including the distribution and localisation of key components in the skin e.g. fatty acids, ceramides and natural moisturising factors.
• Demonstrate the permeation of a commercially important anti-aging peptide into human stratum corneum.
Subjects (LCSH)
Subjects (MeSH)
Subjects
Subjects (JACS)
Subjects (LC)
Divisions
University of Nottingham, UK Campus::Faculty of Science::School of Pharmacy
Corporate collaborators
Walgreens Boots Alliance
Data type
3D mass spectrometry files (itm), Graphs, Images
Funders
Funders
Innovate
ICASE
CDT
ICASE Instrument Grant
Data collection method
3D OrbiISIMS, ION ToF, Excel, GraphPad, Mathlab
Resource languages
English
Publisher
The University of Nottingham
Date Issued
March 18, 2022
Except where otherwise noted, this item's license is described as
File(s)![Thumbnail Image]()
![Thumbnail Image]()
Name
PNAS Raw Data.zip
Size
618.82 MB
Format
Unknown
Checksum (MD5)
60db5bf9218dd2aad739c37270936c4b
Name
PNAS Raw Data.zip
Size
618.82 MB
Format
Unknown
Checksum (MD5)
60db5bf9218dd2aad739c37270936c4b